Effects of Creatine Supplementation on Renal Function: A Systematic Review and Meta-Analysis.
Alexandre de Souza E Silva; Adriana Pertille; Carolina Gabriela Reis Barbosa; Jasiele Aparecida de Oliveira Silva; Diego Vilela de Jesus; Anna Gabriela Silva Vilela Ribeiro; Ronaldo Júlio Baganha; José Jonas de Oliveira
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2019
SR / meta-analysisClosed (all rights reserved)Data current as of 25 Oct 2026
Metadata only. The abstract is not shown here; read it at the publisher or on PubMed.
Abstract
The abstract is not shown here because of the article's licence. Read it on PubMed.
Where this study is used
- Creatine monohydrate supplementation: Kidney function markers (Adults) — Low. Counted in the grade.
Extracted values
AI-assisted extraction: each number comes with the sentence it was read from.
- Studies pooled
- 15
| Field | Value | Source sentence |
|---|---|---|
| Review question | Therefore, this is the first systematic review and meta-analysis study that aimed to investigate creatine supplements and their possible renal function side effects. | Show quote for Review questionTherefore, this is the first systematic review and meta-analysis study that aimed to investigate creatine supplements and their possible renal function side effects. Located at |
| Intervention · Agent | creatine supplements | Show quote for Intervention · Agentinvestigate creatine supplements Located at |
| N studies | 15 | Show quote for N studies15 were included in the qualitative analysis Located at |
serum creatinine levels
SMD 0.48 (95% CI 0.24 to 0.73) · P = 0.001
| Field | Value | Source sentence |
|---|---|---|
| Outcome name | serum creatinine levels | Show quote for Outcome namecreatine supplementation did not significantly alter serum creatinine levels Located at |
| Effect measure | SMD | Show quote for Effect measurestandardized mean difference = 0.48 Located at |
| Effect measure as written | standardized mean difference | Show quote for Effect measure as writtenstandardized mean difference = 0.48 Located at |
| Point estimate | 0.48 | Show quote for Point estimatestandardized mean difference = 0.48 Located at |
plasma urea values
SMD 1.1 (95% CI 0.34 to 1.85) · P = 0.004
| Field | Value | Source sentence |
|---|---|---|
| Outcome name | plasma urea values | Show quote for Outcome namedid not alter plasma urea values Located at |
| Effect measure | SMD | Show quote for Effect measurestandardized mean difference = 1.10 Located at |
| Effect measure as written | standardized mean difference | Show quote for Effect measure as writtenstandardized mean difference = 1.10 Located at |
| Point estimate | 1.1 | Show quote for Point estimatestandardized mean difference = 1.10 Located at |
How these values were extracted
Model claude-haiku-5-5+claude-sonnet-5-5, run on 26 Oct 2026. 2 passes, 95% agreement between passes. 0 fields checked by a person.