Protein interventions augment the effect of resistance exercise on appendicular lean mass and handgrip strength in older adults: a systematic review and meta-analysis of randomized controlled trials.

Richard P Kirwan; Mohsen Mazidi; Carmen Rodríguez García; Katie E Lane; Alireza Jafari; Tom Butler; Fatima Perez de Heredia; Ian G Davies

The American journal of clinical nutrition, 2022

Metadata only. The abstract is not shown here; read it at the publisher or on PubMed.

Abstract

The abstract is not shown here because of the article's licence. Read it on PubMed.

Read the abstract on PubMed

Where this study is used

Protein supplementation in older adults: Lean / fat-free mass (Older adults) — Low. Counted in the grade.
Protein supplementation in older adults: Lean / fat-free mass (Older adults with resistance training) — Low. Counted in the grade.
Protein supplementation in older adults: Lower-body strength (Older adults) — Low. Counted in the grade.

Extracted values

AI-assisted extraction: each number comes with the sentence it was read from.

Studies pooled: 28

Study-level values with their source sentences
Field	Value	Source sentence
Review question	We assessed the evidence on the effects of whole protein supplementation or higher-protein diets, without the use of amino acids or supplements known to stimulate hypertrophy, alone or in combination with resistance exercise (RE) interventions, on lean body mass (LBM) and strength in older adults.	Show quote for Review question We assessed the evidence on the effects of whole protein supplementation or higher-protein diets, without the use of amino acids or supplements known to stimulate hypertrophy, alone or in combination with resistance exercise (RE) interventions, Located at `abs:OBJECTIVES/s:0`
Population	older adults (mean age ≥50 y)	Show quote for Population in older adults (mean age ≥50 y) Located at `abs:METHODS/s:1`
Intervention · Agent	whole protein supplementation or higher-protein diets	Show quote for Intervention · Agent effects of whole protein supplementation or higher-protein diets

Protein interventions augment the effect of resistance exercise on appendicular lean mass and handgrip strength in older adults: a systematic review and meta-analysis of randomized controlled trials.

Richard P Kirwan; Mohsen Mazidi; Carmen Rodríguez García; Katie E Lane; Alireza Jafari; Tom Butler; Fatima Perez de Heredia; Ian G Davies

The American journal of clinical nutrition, 2022

Metadata only. The abstract is not shown here; read it at the publisher or on PubMed.

Extracted values

AI-assisted extraction: each number comes with the sentence it was read from.

Studies pooled: 28

Study-level values with their source sentences
Field	Value	Source sentence
Review question	We assessed the evidence on the effects of whole protein supplementation or higher-protein diets, without the use of amino acids or supplements known to stimulate hypertrophy, alone or in combination with resistance exercise (RE) interventions, on lean body mass (LBM) and strength in older adults.	Show quote for Review question We assessed the evidence on the effects of whole protein supplementation or higher-protein diets, without the use of amino acids or supplements known to stimulate hypertrophy, alone or in combination with resistance exercise (RE) interventions, Located at `abs:OBJECTIVES/s:0`
Population	older adults (mean age ≥50 y)	Show quote for Population in older adults (mean age ≥50 y) Located at `abs:METHODS/s:1`
Intervention · Agent	whole protein supplementation or higher-protein diets	Show quote for Intervention · Agent effects of whole protein supplementation or higher-protein diets

Field	Value	Source sentence
Outcome name	total LBM	Show quote for Outcome name total LBM [weighted mean difference in change (WMD): 0.34; 95% CI: -0.21, 0.89; I2 = 90.01%] Located at `abs:RESULTS/s:1`
Effect measure	WMD	Show quote for Effect measure weighted mean difference in change (WMD): 0.34 Located at `abs:RESULTS/s:1`
Effect measure as written	weighted mean difference in change (WMD)	Show quote for Effect measure as written weighted mean difference in change (WMD): 0.34 Located at `abs:RESULTS/s:1`
Point estimate	0.34	Show quote for Point estimate total LBM [weighted mean difference in change (WMD): 0.34; 95% CI: -0.21, 0.89; I2 = 90.01%] Located at `abs:RESULTS/s:1`
Ci low	−0.21	Show quote for Ci low total LBM [weighted mean difference in change (WMD): 0.34; 95% CI: -0.21, 0.89; I2 = 90.01%] Located at `abs:RESULTS/s:1`
Ci high	0.89	Show quote for Ci high total LBM [weighted mean difference in change (WMD): 0.34; 95% CI: -0.21, 0.89; I2 = 90.01%] Located at `abs:RESULTS/s:1`
Ci level	95	Show quote for Ci level 95% CI: -0.21, 0.89 Located at `abs:RESULTS/s:1`
I2	90.01	Show quote for I2 I2 = 90.01% Located at `abs:RESULTS/s:1`
Analysis kind	primary	Show quote for Analysis kind In pooled analysis Located at `abs:RESULTS/s:1`

Field	Value	Source sentence
Outcome name	ALM	Show quote for Outcome name ALM (WMD: 0.4; 95% CI: -0.01, 0.81; I2 = 90.38%) Located at `abs:RESULTS/s:1`
Effect measure	WMD	Show quote for Effect measure ALM (WMD: 0.4; 95% CI: -0.01, 0.81; I2 = 90.38%) Located at `abs:RESULTS/s:1`
Effect measure as written	WMD	Show quote for Effect measure as written WMD: 0.4 Located at `abs:RESULTS/s:1`
Point estimate	0.4	Show quote for Point estimate ALM (WMD: 0.4; 95% CI: -0.01, 0.81; I2 = 90.38%) Located at `abs:RESULTS/s:1`
Ci low	−0.01	Show quote for Ci low ALM (WMD: 0.4; 95% CI: -0.01, 0.81; I2 = 90.38%) Located at `abs:RESULTS/s:1`
Ci high	0.81	Show quote for Ci high ALM (WMD: 0.4; 95% CI: -0.01, 0.81; I2 = 90.38%) Located at `abs:RESULTS/s:1`
Ci level	95	Show quote for Ci level 95% CI: -0.01, 0.81 Located at `abs:RESULTS/s:1`
I2	90.38	Show quote for I2 I2 = 90.38% Located at `abs:RESULTS/s:1`
Analysis kind	primary	Show quote for Analysis kind In pooled analysis Located at `abs:RESULTS/s:1`

Field	Value	Source sentence
Outcome name	HG strength	Show quote for Outcome name HG strength (WMD: 0.69; 95% CI: -0.69, 2.06; I2 = 94.52%) Located at `abs:RESULTS/s:1`
Effect measure	WMD	Show quote for Effect measure HG strength (WMD: 0.69; 95% CI: -0.69, 2.06; I2 = 94.52%) Located at `abs:RESULTS/s:1`
Effect measure as written	WMD	Show quote for Effect measure as written WMD: 0.69 Located at `abs:RESULTS/s:1`
Point estimate	0.69	Show quote for Point estimate HG strength (WMD: 0.69; 95% CI: -0.69, 2.06; I2 = 94.52%) Located at `abs:RESULTS/s:1`
Ci low	−0.69	Show quote for Ci low HG strength (WMD: 0.69; 95% CI: -0.69, 2.06; I2 = 94.52%) Located at `abs:RESULTS/s:1`
Ci high	2.06	Show quote for Ci high HG strength (WMD: 0.69; 95% CI: -0.69, 2.06; I2 = 94.52%) Located at `abs:RESULTS/s:1`
Ci level	95	Show quote for Ci level 95% CI: -0.69, 2.06 Located at `abs:RESULTS/s:1`
I2	94.52	Show quote for I2 I2 = 94.52% Located at `abs:RESULTS/s:1`
Analysis kind	primary	Show quote for Analysis kind In pooled analysis Located at `abs:RESULTS/s:1`

Field	Value	Source sentence
Outcome name	KE strength	Show quote for Outcome name KE strength (WMD: 1.88; 95% CI: -0.6, 4.35; I2 = 95.35%) Located at `abs:RESULTS/s:1`
Effect measure	WMD	Show quote for Effect measure KE strength (WMD: 1.88; 95% CI: -0.6, 4.35; I2 = 95.35%) Located at `abs:RESULTS/s:1`
Effect measure as written	WMD	Show quote for Effect measure as written WMD: 1.88 Located at `abs:RESULTS/s:1`
Point estimate	1.88	Show quote for Point estimate KE strength (WMD: 1.88; 95% CI: -0.6, 4.35; I2 = 95.35%) Located at `abs:RESULTS/s:1`
Ci low	−0.6	Show quote for Ci low KE strength (WMD: 1.88; 95% CI: -0.6, 4.35; I2 = 95.35%) Located at `abs:RESULTS/s:1`
Ci high	4.35	Show quote for Ci high KE strength (WMD: 1.88; 95% CI: -0.6, 4.35; I2 = 95.35%) Located at `abs:RESULTS/s:1`
Ci level	95	Show quote for Ci level 95% CI: -0.6, 4.35 Located at `abs:RESULTS/s:1`
I2	95.35	Show quote for I2 I2 = 95.35% Located at `abs:RESULTS/s:1`
Analysis kind	primary	Show quote for Analysis kind In pooled analysis Located at `abs:RESULTS/s:1`

Field	Value	Source sentence
Outcome name	ALM	Show quote for Outcome name ALM (WMD: 0.54; 95% CI: 0.03, 1.05; I2 = 89.76%) Located at `abs:RESULTS/s:2`
Effect measure	WMD	Show quote for Effect measure WMD: 0.54 Located at `abs:RESULTS/s:2`
Effect measure as written	WMD	Show quote for Effect measure as written WMD: 0.54 Located at `abs:RESULTS/s:2`
Point estimate	0.54	Show quote for Point estimate WMD: 0.54 Located at `abs:RESULTS/s:2`
Ci low	0.03	Show quote for Ci low 95% CI: 0.03, 1.05 Located at `abs:RESULTS/s:2`
Ci high	1.05	Show quote for Ci high 95% CI: 0.03, 1.05 Located at `abs:RESULTS/s:2`
Ci level	95	Show quote for Ci level 95% CI: 0.03, 1.05 Located at `abs:RESULTS/s:2`
I2	89.76	Show quote for I2 I2 = 89.76% Located at `abs:RESULTS/s:2`
Subgroup	interventions that used also RE	Show quote for Subgroup in interventions that used also RE Located at `abs:RESULTS/s:2`
Analysis kind	subgroup	Show quote for Analysis kind in interventions that used also RE Located at `abs:RESULTS/s:2`

Protein interventions augment the effect of resistance exercise on appendicular lean mass and handgrip strength in older adults: a systematic review and meta-analysis of randomized controlled trials.

Abstract

Where this study is used

Extracted values

Protein interventions augment the effect of resistance exercise on appendicular lean mass and handgrip strength in older adults: a systematic review and meta-analysis of randomized controlled trials.

Abstract

Where this study is used

Extracted values

total LBM

ALM

HG strength

KE strength

ALM · interventions that used also RE

HG · interventions that used also RE

ALM · sarcopenic/frail populations

How these values were extracted

Field	Value	Source sentence
Outcome name	HG	Show quote for Outcome name HG (WMD: 1.71; 95% CI: 0.12, 3.30; I2 = 88.71%) Located at `abs:RESULTS/s:2`
Effect measure	WMD	Show quote for Effect measure WMD: 1.71 Located at `abs:RESULTS/s:2`
Effect measure as written	WMD	Show quote for Effect measure as written WMD: 1.71 Located at `abs:RESULTS/s:2`
Point estimate	1.71	Show quote for Point estimate WMD: 1.71 Located at `abs:RESULTS/s:2`
Ci low	0.12	Show quote for Ci low 95% CI: 0.12, 3.30 Located at `abs:RESULTS/s:2`
Ci high	3.3	Show quote for Ci high 95% CI: 0.12, 3.30 Located at `abs:RESULTS/s:2`
Ci level	95	Show quote for Ci level 95% CI: 0.12, 3.30 Located at `abs:RESULTS/s:2`
I2	88.71	Show quote for I2 I2 = 88.71% Located at `abs:RESULTS/s:2`
Subgroup	interventions that used also RE	Show quote for Subgroup in interventions that used also RE Located at `abs:RESULTS/s:2`
Analysis kind	subgroup	Show quote for Analysis kind in interventions that used also RE Located at `abs:RESULTS/s:2`

Field	Value	Source sentence
Outcome name	ALM	Show quote for Outcome name effects on ALM occurred only in sarcopenic/frail populations (WMD: 0.88; 95% CI: 0.51, 1.25; I2 = 79.0%) Located at `abs:RESULTS/s:4`
Effect measure	WMD	Show quote for Effect measure effects on ALM occurred only in sarcopenic/frail populations (WMD: 0.88; 95% CI: 0.51, 1.25; I2 = 79.0%) Located at `abs:RESULTS/s:4`
Effect measure as written	WMD	Show quote for Effect measure as written WMD: 0.88 Located at `abs:RESULTS/s:4`
Point estimate	0.88	Show quote for Point estimate effects on ALM occurred only in sarcopenic/frail populations (WMD: 0.88; 95% CI: 0.51, 1.25; I2 = 79.0%) Located at `abs:RESULTS/s:4`
Ci low	0.51	Show quote for Ci low effects on ALM occurred only in sarcopenic/frail populations (WMD: 0.88; 95% CI: 0.51, 1.25; I2 = 79.0%) Located at `abs:RESULTS/s:4`
Ci high	1.25	Show quote for Ci high effects on ALM occurred only in sarcopenic/frail populations (WMD: 0.88; 95% CI: 0.51, 1.25; I2 = 79.0%) Located at `abs:RESULTS/s:4`
Ci level	95	Show quote for Ci level 95% CI: 0.51, 1.25 Located at `abs:RESULTS/s:4`
I2	79	Show quote for I2 I2 = 79.0% Located at `abs:RESULTS/s:4`
Subgroup	sarcopenic/frail populations	Show quote for Subgroup only in sarcopenic/frail populations Located at `abs:RESULTS/s:4`
Analysis kind	subgroup	Show quote for Analysis kind Subgroup analysis revealed Located at `abs:RESULTS/s:4`